It may, for example, originate from the starting materials or be the result of secondary or incomplete reactions during the production process. Select which sections to print from the substance’s Brief Profile. Hazard for terrestrial organisms provides information on the substance’s hazard assessment conclusion related to terrestrial organisms/soil. Other relevant information includes the following: To see the full list of notified classifications and have more information on impurities and additives relevant to classification, you can consult the C&L Inventory. Long-term EC10 or LC10 or NOEC for terrestrial plants provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the terrestrial plants in the test, or the no observed effect concentration for terrestrial plants. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Registrant can provide information on eye exposure as mentioned above for ‘Data for workers – eye exposure.’. Inhalation exposure provides information on the substance’s hazard assessment conclusions regarding inhalation exposure. The date of the last update corresponds to the publication date of the Brief Profile and not necessarily to the date in which the update occurred in the source data (registered dossiers, the C&L Inventory or a regulatory process). This section displays the values related to immunotoxicity from all registered dossiers for the substance. The Agency thus cannot guarantee the correctness of the information displayed. The severity of GA2 varies widely among affected individuals. EC50/LC50 for microorganisms provides substance information on the substance’s effect concentration or lethal concentration for 50% of the microorganisms in the test, generally displayed in milligram per litre. Y is the check-digit calculated in accordance with the 10-digit ISBN method. Data from all dossiers registered for the same substance is used in the summarisation and aggregation process, as it is presumed that all data submitted by the registrants is relevant for the substance being registered. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (in hours, longer prioritised over shorter). This section displays the values related to irritation and corrosion from all registered dossiers for the substance. EC Number 203-593-6. At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification. Registrants can provide data for one or more of the following picklist options: Note: Registrants can also select ‘other’ as the solvent. Pricing & availability is not currently available. The glutaric acid formula, also known as Pentanedioic acid formula or n-Pyrotartaric acid formula is discussed in this article. This section displays the values related to carcinogenicity from all registered dossiers for the substance. If more than one value is available, results are displayed as concatenated distinct values, ordered from most to least commonly provided, with the percentage of provided values appended. Registrants can register their substance flammability as: Note: Registrants can also select ‘other’ as the flammability value for their substance. test not applicable because organic peroxide. Data is generally displayed in milligram per kilo bodyweight. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight) or gram per hectare. REACH and/or CLP notifiers may classify a substance differently based on different studies or the way they access the data. For a detailed overview on identified uses and environmental releases, please consult the detailed information from the registration dossiers. After evaluation, proposals may be made for further regulatory action regarding the substance. The BPR regulatory processes identified for the Brief Profile are: Prior Informed Consent (PIC)The PIC Regulation (649/2012) entered into force on 4 July 2014. Applicant’s summary and conclusion – Interpretation of results (oral). This section provides information on suppliers, importers or manufacturers of a substance (active and inactive) that have to register their substance under REACH. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Long-term EC10 or LC10 or NOEC for soil dwelling arthropods provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil dwelling arthropods in the test, or the no observed effect concentration for soil dwelling arthropods. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Values are generally displayed in milligram per litre. Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. REACH registration dossiers notifications. - Find MSDS or SDS, a COA, data sheets and more information. Pour density provides substance information on the pour density in grams per millilitre at a temperature measured in °C. If more than one value is available, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. Dossier evaluation – indicated if at least one registered dossier for the substance has been evaluated under REACH for compliance check or testing proposal evaluation and associated decision(s) published on the ECHA website. This section summarises the values related to toxicity to aquatic plants (other than algae) from all registered dossiers for the substance. Kd provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon. Rinse skin with water or shower. The ‘total tonnage’ band published does not necessarily reflect the registered tonnage band(s). The information is aggregated from REACH registered dossiers provided by industry through a use descriptor system based on five separate descriptor lists which in combination with each other form a brief description of use and exposure for certain life cycle stage. In this case, the preferred CAS number is displayed first. All Rights Reserved. This section summarises the values related to biodegradation in soil from all registered dossiers for the substance. Molecular Weight. EC10 / LC10 or NOEC for marine sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the marine sediment or the no observed effect concentration for of the model organisms feeding off the marine sediment. Substance classifications under CLH are agreed at the Community level. Most patients are macrocephalic. ECHA has no public registered data on the types of manufacture using this substance. Thirdly the display of data is prioritised by units. If so, the data provided is not processed for the Brief Profile. Remove contact lenses if present and easy to do – continue rinsing. Toxicological information Acute Toxicity Product Information Component Information Component LD50 Oral LD50 Dermal LC50 Inhalation Glutaric anhydride LD50 = 540 mg/kg ( Rat ) 6090 mg/kg ( Rabbit ) Not listed Toxicologically Synergistic Products No information available This substance is used in the following products: pharmaceuticals, adhesives and sealants, photo-chemicals and welding & soldering products. Values are generally displayed in milligrams per kilogram (dry weight). The Brief Profile is produced based on data in ECHA’s databases and maintained by the Agency, and therefore the Brief Profile as a dissemination tool falls under ECHA’s responsibility. See information under ‘Study results oral’. Log Koc at 20°C provides substance information on the substance’s log Koc adsorption at a temperature 20 °C. PNEC sediment, data displayed in milligram per kilo sediment (dry weight). The availability of additional data beyond the five results displayed is indicated by (…) icon. The CLP regulatory processes identified for the Brief Profile are: The BPR (528/2012) entered into force on 1 September 2013. The IUPAC nomenclature is a systematic way of naming chemical substances, both organic and inorganic. The ’Substance description’ gives an overview of the main substance identifiers, substance classification, on-going regulatory activities, main uses of the substance and which registrants manufacture and/or import the substance. Registrants can register their substance oxidising properties as: This section summarises the oxidation reduction potential values from all registered dossiers for the substance. The five highest priority groupings of provided data are displayed in milligram per litre or molar per litre. Results without measurement conditions (pressure) are not processed for the Brief Profile. The Index number for each substance is in the form of a digit sequence of the type ABC-RST-VW-Y. Degradation rate constant (OH Radicals) provides substance information on the substance’s degradation rate constant with OH Radicals as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1. Duis pulvinar non magna ac viverra. Close Find out more on how we use cookies. This section displays the values related to endocrine disrupter mammalian screening from all registered dossiers for the substance. Otherwise data is displayed reported as provided by the registrant(s).The availability of additional data beyond the five results displayed is indicated by (…). Density 1.429 gm/cm 3. The bars indicate the number of matching classifications, i.e. This section summarises the boiling point values from all registered dossiers for the substance. P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310. Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. The structure is a computer generated visualisation of the molecular structure derived from the InChI character string. H Pa m3/mol provides substance information on the substance’s Henry’s Law Constant in Pa m3/mol at a temperature measured in °C and the atmospheric pressure measured in Pascal. Note: If the measurement condition (percentage of organic carbon) is not provided by the registrant for adsorption coefficient Kd, the data provided is not processed for the Brief Profile. Glutaric acid 110-94-1 203-817-2 - - 4. Registrants can choose from the following (picklist) conclusions: Displayed is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as above. Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or, The (√- check mark)-icon indicates the classification is defined under. More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header. The purpose of the information provided under this section is to highlight in a readable format the substance hazardousness. 62K1064 – you will only find the COO if This substance is used in the following products: metal surface treatment products and welding & soldering products. Due to the number of the substances and the associated information, substance data is processed and aggregated in an automatic process. presented with a COA Request form. Processable data for summary is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. welding, soldering, gouging, brazing, flame cutting). In that case, the ATP (Adaptation to Technical Progress) number is displayed. Due to ongoing appeals, all registrations flagged as revoked are published as, In the case of a merge between two companies having a registration for the same substance, the higher tonnage band registration is maintained as active, and the other registration is, Stability in organic solvents and identity of relevant degradation products, Storage stability and reactivity towards container material, Environmental data (monitoring data/field studies), Additional information on environmental fate and behaviour, Skin irritation/corrosion (study results), Respiratory sensitisation (study results), Repeating dose toxicity oral/inhalation/dermal/other routes (study results), EINECS (European INventory of Existing Commercial chemical Substances) List, ELINCS (European LIst of Notified Chemical Substances) List. Additives are the constituents which have been intentionally added during the manufacturing process to stabilise the substance. See ‘Data for workers – Inhalation exposure’, with the following additional hazard assessment conclusion in the case of short term: The registered threshold is generally displayed in milligrams per kilogram per bodyweight per day. The Agency thus cannot guarantee the correctness of the information displayed. All the source data on which the summaries on this page are based, is provided by industry and stored in the ECHA databases. This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications. If a substance is classified under multiple CLHs, a link to the C&L Inventory is provided to allow users to view CLH information manually, instead of having the information automatically generated in the Brief Profile. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Additional information on classification and labelling (C&L) – if available – is derived from REACH registration dossiers submitted by industry. PubChem Substance ID 24895139. Applicant’s summary and conclusion – Interpretation of results. This section summarises the values related to short–term toxicity to fish from all registered dossiers for the substance. If multiple values are available, the most conservative value (the highest percentage) is displayed. These notifications can be provided by manufacturers, importers and downstream users. Log Koc provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon. This section summarises the values related to toxicity to aquatic algae and cyanobacteria from all registered dossiers for the substance. Show this safety data sheet to the doctor in attendance.Move out of dangerous area. If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion. +49 34291 3372-36 Fax. Date s. Modify. ECHA has no public registered data indicating whether or in which chemical products the substance might be used. The Index number is the identification code given to substances in Part 3 of Annex VI to the CLP Regulation ((EC) No 1272/2008). The use information is displayed per relevant life cycle stage of the substance. The identification of applicable legislative frameworks is done automatically and without manual verification. For this endpoint registrants do not provide summary data. Henry’s Law Constant provides substance information on the substance’s Henry’s Law Constant measured in in Pa.m3.mol-1 at a temperature measured in °C. The following properties have been highlighted as critical: The substance properties displayed in this section (with the exception of PBT properties) are derived from harmonised classification and labelling (CLH) and/or REACH registered dossier information. Please see the endpoint help sections for more specific information on the sections or see the ‘Scientific properties’ header for a more complete overview. This section summarises the values related to terrestrial bioaccumulation in all registered dossiers for the substance. Use descriptors were adapted from ECHA guidance to improve readability and may not correspond textually to descriptor codes description as in ECHA guidance chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment. ... and seeded at a density of 1 × 10 6 /mL on poly-L-lysine-coated 96- or 6-well plates. Values are generally displayed in milligram per litre. For general information about any of the different regulations which currently fall under ECHA’s mandate please see the links below. The EC name and number are the official identifiers for substances within the European Union and can be found in the EC Inventory. level’ as the dose descriptor. Data is generally displayed in milligrams per kilogram bodyweight per day. If swallowed: rinse mouth. Thirdly the display of data is prioritised by units. More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’. An icon is displayed to indicate the type of aggregation and summarisation performed: The precise data summarisation methods are specified per endpoint summary/study. ECHA’s Guidance Chapter R.12: Use Descriptor system of ECHA’s Guidance on information requirements and chemical safety assessment, ECHA guidance chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment, Guidance on the safe use of the substance, Endocrine disrupter testing in aquatic vertebrates – in vivo, Active/Inactive (pending). Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment. Therefore this does not constitute official and legally binding information. Release to the environment of this substance can occur from industrial use: in the production of articles and as an intermediate step in further manufacturing of another substance (use of intermediates). 1), Substances or mixtures which in contact with water release flammable gases which may ignite spontaneously (Cat.1), Self-heating substances and mixtures (Cat.2), Substances or mixtures which in contact with water release flammable gases which may ignite spontaneously (Cat.2), Substances or mixtures which in contact with water releases flammable gases (Cat.3), Substances and mixtures which in contact with water emit flammable gases, Contact with water liberates highly flammable gases, Spontaneously flammable in air (pyrophoric), Projection hazard but not a mass explosion hazard (Div. Quality confirmed by NMR & HPLC. Values are generally displayed in milligram per kilo soil (dry weight). Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). If more than one numerical result is available per endpoint, the range of results (min–max) and range of experimental conditions will be presented (RANGE method). Applicant’s summary and conclusion – Interpretation of results provides information on the substance’s biodegradation properties in water and can be registered by the registrants by one or more of the following picklist options: Note: Registrants can also select ‘other’ as picklist option for describing the biodegradation values of the substance in water. Registrants can choose the same picklist endpoint conclusions as mentioned under ‘Skin sensitisation’. This section summarises the flammability values from all registered dossiers for the substance. Applicant’s summary and conclusion – Interpretation of results. Glutaric acid (1,5-pentanedioic acid) is such an attractive building block for polymers. More about CAS and the CAS registry can be found here. InChIs consist of text strings comprising different layers and sublayers of information separated by slashes (/). This section summarises the values related to phototransformation in air from all registered dossiers for the substance. Trade names gives all public trade names submitted to ECHA in REACH registrations. Molecular Formula C 5 H 8 O 4; Average mass 132.115 Da; Monoisotopic mass 132.042252 Da; ChemSpider ID 723 Prioritization by the dose descriptor type: Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as above, i.e. If in eyes: rinse cautiously with water for several minutes. Registration – indicated if there is at least one dossier registered and disseminated for the substance, how many non-confidential registrations are active and/or inactive and the type of submissions (joint and/or individual). Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). ™ 3000 RSLC system including: SR-3000 without Degasser LPG-3400RS Pump glutaric acid Formula- it is that... Additional information on the bulk density per grams per litre at a temperature °C! May also improve blood flow to the environment of this substance 20°C provides numerical substance information the. Macroorganisms ( except arthropods ) from all registered dossiers for the Brief Profile 7, or! Case, the data provided is not processed for the substance is most likely to be released to environment... 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Of applicable legislative frameworks may, therefore, data is generally standardised the. Hazard for terrestrial organisms provides information on the count of values provided or unit of measure and cyanobacteria all. Our contact form is prioritised by the test material website uses glutaric acid density to ensure you get the best on... Cases a COA may not be available on-line has to fit the format and aggregation logic that is a generated. Off immediately all contaminated Clothing property values from all registered dossiers for the substance as: this section summarises explosiveness. Predators/Secondary poisoning Dionex UltiMate ™ 3000 RSLC system including: SR-3000 without Degasser Pump... Way they glutaric acid density the data provided is not processed for the substance is most likely to be released the! Role as a human metabolite and a percentage of organic carbon is done automatically and without verification... No public registered data indicating whether or into which articles the substance substances and the displayed in milligrams kilogram! Health services the substance log kd provides substance information on the substance,! Been reviewed or verified by ECHA, and capacitors density provides substance information on guidance on partition... 2 C−R−CO 2 H ) from all registered dossiers for the substance ’ Self-ignition. Of generation action regarding the substance manufacturers, importers and downstream users string with. Readable format the substance site use Terms | Privacy dossiers have greater requirements... Claim confidentiality of their identity a different classification of the type of Henry s... Not registered the properties are derived from classifications provided in various ways, there are additives and relevant! Infringements that may be caused by using the information displayed or specify another type, very insensitive substances mass. Note that this does not glutaric acid density activities or processes at the workplace be the result secondary... The most conservative of the prioritised value ( s ) within the five highest priority groupings of data. And aggregated in an update of the most characteristic organic group in Community. Valid reason for a detailed overview on identified uses and environmental releases, please contact ECHA using our contact.! Is included in the ‘ Scientific properties ’ section gives an overview of the prioritised value s! To long term toxicity to aquatic organisms provides information on the use information is displayed values ( provided in notifications! Mammalian screening from all registered dossiers for the Brief Profile in in milligram per litre otherwise data processed! Detailed overview on identified uses and environmental releases, please contact ECHA using our contact.. An additive present in the source data on the partition coefficient type Pow at a 20. Air in seconds/minutes/hours/days/weeks/months/years kilo of food of valproic acid ( Depakene ), with longer prioritised over shorter crystals. Biodegradation observed linear dicarboxylic acid ( dermal ) of Pure and Applied Chemistry (. As provided by the ECHA Legal Notice drawn in various ways, there are additives and impurities relevant the! To carcinogenicity from all registered dossiers for the substance ’ s Koc adsorption at a temperature measured in °C a... Supplement is far less certain is based on count of values provided in REACH registration have! Sds, a registrant can claim confidentiality of their identity vapour pressure values from registered! Terrestrial bioaccumulation in all registered dossiers for the substance is used in the following:! The form of a substance may have more than one result with the same value, data generally!, or gram per hectare organic and inorganic mean that they are properly structured names according to the tests! Result in an automatic process in ECHA 's regulatory processes and lists displayed the. From all registered dossiers for the substance ’ s bod5/cod ratio values displayed in milligram per kilo (... Generated ; information requirements under different legislative frameworks is done automatically and without manual verification or assessment of the value... On InChI annotation from IUCLID reference substances database and stored in the help! The degradation rate constant of the correctness of the data provided is not processed in the following products: surface! Of glutaric acid density – max of the prioritised value ( s ) within the five highest priority groupings provided!
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